The Mucosal Pathogens Research Unit is an exciting translational programme that addresses limitations on the long-term effectiveness of existing vaccines through new approaches to interrupting pathogen carriage and transmission in African lower and middle-income countries.  We focus on mucosal pathogens causing pneumonia, meningitis, and neonatal sepsis, which account for more than 2 million deaths each year globally.

The MPRU has forged partnerships with the Universities of Edinburgh, Oxford, Cambridge and Southampton, Liverpool School of Tropical Medicine, London School of Hygiene and Tropical Medicine, St George's University of London, BUGS Bioscience and Wellcome Sanger Institute in the UK with research centres in Malawi, Kenya, Mali, South Africa, The Gambia, Uganda, Ghana, Côte d'Ivoire, and Nigeria bringing together more than 25 senior investigators with strong ongoing research portfolios. Linking many of the best in the field, the MPRU will take a transformative approach to the prevention of life-threatening disease caused by mucosal pathogens that could not be achieved by individual investigators or institutions.


MPRU Theory of Change


MPRU partner map