Paper on microbiome and malnutrition published in EBioMedicine
Congratulations to MPRU postdoctoral research associate Dr Brenda Kwambana-Adams and colleagues on their recent publication in EBioMedicine! Brenda is one of the corresponding authors on this study examining the enteric microbiome, pathogen abundance and energy regulating hormones in Gambian children between 6-24 months of age. Using inter- and intramodality association networks coupled with sequencing and clinical measurements, the investigators found lower microbial richness and increased Enterobacteriaceae, including genes associated with EPEC, in children with non-edematous severe acute malnutrition. They also discovered higher levels of [soluble leptin receptor]/[leptin] ratio in children with more severe malnutrition than in well-nourished children. Please read the full report on the publisher's site.