Paper on pneumococcal strain sharing out in Microbial Genomics

16 Feb 2022

Congratulations to MPRU senior research fellow Dr Brenda Kwambana-Adams and colleagues on their recent publication in Microbial Genomics! Brenda and co-authors calculated genomic pairwise distance of pneumococcal strains isolated from infants during a longitudinal birth cohort study in rural Gambia. By combining genomic analyses with metadata on infant location and the nature of colonization (sustained vs transient), they showed that sustained strain sharing was more likely to occur in infants living within a 5km radius of each other. This finding suggests that repeated exposure may play a role in sustained pneumococcal carriage. Please find the full paper at the publisher's site.