Review on possibility of a common vaccine against S. agalactiae and S. pneumoniae published in Frontiers in Microbiology

08 Oct 2021

Congratulations to MPRU collaborator Dr Kanny Diallo, MPRU postdoctoral associate Dr Andrea Gori and MPRU master's student Edmund Bedeley for their recent publication in Frontiers in Microbiology! The review explored the possibility of generating a common vaccine against Streptococcus agalactiae (also known as Group B Streptococcus or GBS) and Streptococcus pneumoniae, two mucosal pathogens that cause significant mortality in low-middle income countries. By interrogating the literature, the authors identified several structurally similar proteins and structures that could be included in a vaccine formulation - these include the GBS β protein, S. pneumoniae PspC protein, pili and serine rich repeat proteins. They also proposed bioinformatic methods that could help unearth additional commonalities between these two species. Please find the full review at the publisher's site.